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【目的】了解临沧市儿童接种乙肝疫苗后乙型肝炎病毒表面抗体(HBsAb)在不同年份、不同性别、不同年龄段的阳性率。【方法】用金标法对11 104名儿童进行末梢血HBsAb检测,并按年份、年龄、性别分组进行统计分析。【结果】11 104名儿童中,HBsAb总阳性率为79.1%,2009年,～1岁年龄组HBsAb的阳性率最高94%,2006年,～7岁年龄组的HBsAb阳性率最低46.8%,HBsAb阳性率在不同年龄组之间、不同年份之间有显著的统计学意义,男童组与女童组之间无统计学意义。【结论】儿童HBsAb的总阳性率逐年提高,但有随年龄的增长而下降的趋势。因此定期检测HBsAb,适时加强接种乙肝疫苗是提高儿童HBsAb阳性率的关键。
【Objective】 To understand the positive rate of hepatitis B virus surface antigen (HBsAb) in children of different years, different genders and different ages after inoculation of hepatitis B vaccine in children in Lincang. 【Method】 The gold standard method was used to detect 11 104 children’s peripheral blood HBsAb, and statistical analysis was made by year, age and sex. 【Results】 The total positive rate of HBsAb in 11 104 children was 79.1%. In 2009, the highest positive rate of HBsAb in the age group of 1 year was 94%. In 2006, the positive rate of HBsAb in the age group of 7 years was the lowest, 46.8%, while the positive rate of HBsAb The positive rate in different age groups, between different years was statistically significant, boys and girls group was not statistically significant. 【Conclusion】 The total positive rate of HBsAb in children increases year by year, but decreases with age. Therefore, the regular detection of HBsAb, timely hepatitis B vaccination is to raise the key to the positive rate of HBsAb in children.