壳聚糖宫颈抗菌膜治疗宫颈病变的临床研究

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目的:观察宫颈物理治疗后应用壳聚糖抗菌膜促使创面愈合、减少术后并发症的临床效果。方法:选择因宫颈病变需行激光治疗的200例患者和LEEP治疗的100例患者,两组各随机再分为两组,激光组采用壳聚糖宫颈抗菌膜100例为实验组,激光自然修复100例为对照组,LEEP或冷刀锥切组采用壳聚糖宫颈抗菌膜50例为实验组,LEEP或冷刀锥切自然修复50例为对照组。结果:实验组阴道出血量、持续时间及阴道流液少于对照组(P<0.01),创面愈合率较对照组高(P<0.01),且LEEP组更为明显。结论:物理治疗后联合应用壳聚糖抗菌膜可减少创面渗出、出血和提高创面愈合率,减轻患者的痛苦,提高患者的生活质量。 Objective: To observe the clinical effect of applying chitosan antiseptic membrane to wound healing and reducing postoperative complications after cervical physical therapy. Methods: Two hundred patients with laser lesions treated by laser and 100 patients treated by LEEP were selected. The two groups were randomly divided into two groups. In the laser group, 100 cases of chitosan cervical antimicrobial film were used as the experimental group, 100 cases of control group, LEEP or cold knife taper cut group using chitosan cervical antibacterial membrane 50 cases as the experimental group, LEEP or cold knife conization 50 cases of natural repair as the control group. Results: The amount of vaginal bleeding, duration and vaginal fluid in the experimental group were less than those in the control group (P <0.01). The wound healing rate was higher in the experimental group than in the control group (P <0.01), and the LEEP group was more obvious. Conclusion: The combined application of chitosan antibacterial membrane after physical therapy can reduce wound exudation, bleeding and wound healing rate, alleviate the suffering of patients and improve the quality of life of patients.
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