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目的:分析辛伐他汀(不同给药剂量)对于高血压并高血脂患者血清内皮功能的影响。方法:抽取我院2016年1月-2017年1月收治的102例高血压并高血脂患者,随机分为常规组与实验组,每组各51例,辛伐他汀给药剂量分别为20mg与40mg,对比两组的治疗效果。结果:治疗后实验组的血脂水平改善情况比常规组明显较优,实验组血清内皮功能改善情况相比常规组明显较优,P<0.05。结论:对高血压并高血脂患者建议采取较大剂量的辛伐他汀进行治疗,利于改善血脂与内皮功能,疗效显著,值得临床推广应用。
Objective: To analyze the effect of simvastatin (different doses) on serum endothelial function in patients with hypertension and hyperlipidemia. Methods: A total of 102 patients with hypertension and hyperlipidemia admitted to our hospital from January 2016 to January 2017 were randomly divided into routine and experimental groups, with 51 patients in each group. The doses of simvastatin were 20 mg and 40mg, comparing the treatment effect of two groups. Results: After treatment, the improvement of blood lipid level in the experimental group was better than that in the conventional group. The improvement of serum endothelial function in the experimental group was better than that in the conventional group (P <0.05). Conclusion: It is recommended that simvastatin should be given to patients with hypertension and hyperlipidemia to improve blood lipid and endothelial function, which is worthy of clinical application.