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目的:研究氟康唑联合苦参碱栓对霉菌性阴道炎的治疗效果。方法:纳入我院2015年2月-2017年1月霉菌性阴道炎患者92例并根据治疗方法分组,每组46例,单一治疗组采用氟康唑治疗;联合治疗组采用氟康唑联合苦参碱栓治疗。就两组患者阴道疼痛、黏膜充血、外阴瘙痒消失时间、霉菌性阴道炎治疗效果、治疗前后QOL评分进行比较。结果:联合治疗组霉菌性阴道炎治疗效果明显高于单一治疗组,P<0.05。联合治疗组患者阴道疼痛、黏膜充血、外阴瘙痒消失时间均明显短于单一治疗组,P<0.05。治疗前两组QOL评分比较无显著差异,P>0.05;治疗后联合治疗组QOL评分增幅更大,P<0.05。结论:氟康唑联合苦参碱栓对霉菌性阴道炎的治疗效果确切,可有效改善患者病情,加速症状消退,提高生活质量,值得推广。
Objective: To study the therapeutic effect of fluconazole combined with matrine suppository on mycotic vaginitis. Methods: Ninety-two patients with mycotic vaginitis were included in our hospital from February 2015 to January 2017. The patients in each group were divided into treatment group (n = 46) and fluconazole (single-treatment group). Combination therapy with fluconazole Ginseng treatment. On the two groups of patients with vaginal pain, mucosal hyperemia, genital itching disappear time, the treatment of fungal vaginitis, QOL scores before and after treatment were compared. Results: The treatment effect of mycotic vaginitis in combination therapy group was significantly higher than that in single therapy group (P <0.05). Vaginal pain, mucosal congestion and disappearance of vulvar pruritus were significantly shorter in the combined treatment group than in the single treatment group (P <0.05). There was no significant difference in QOL score between the two groups before treatment (P> 0.05). After treatment, the QOL score of combined treatment group increased more significantly (P <0.05). Conclusion: Fluconazole combined with matrine suppository has definite therapeutic effect on mycotic vaginitis, which can effectively improve the patient’s condition, accelerate the regression of symptoms and improve the quality of life, which deserves promotion.