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目的:评价雷尼替丁联合蛇毒凝血酶注射液治疗老年上消化道出血的临床疗效。方法:85例≥60岁老年上消化道出血患者随机分为2组,对照组42例,患者胃管内注入凝血酶,同时静注雷尼替丁;观察组43例,静注蛇毒凝血酶和雷尼替丁。比较两组临床疗效、平均出血时间及治疗过程中的不良反应。结果:观察组消化道出血停止平均时间为(16.8±5.7)h,总有效率为97.67%,与对照组比较,差异均有统计学意义(P<0.05),治疗过程中无明显不良反应发生。结论:雷尼替丁联合蛇毒凝血酶注射液治疗老年患者消化道出血疗效确切,作用迅速,安全可靠,值得推广使用。
Objective: To evaluate the clinical efficacy of ranitidine combined with snake venom thrombin injection in elderly patients with upper gastrointestinal bleeding. Methods: Eighty-five elderly patients with upper gastrointestinal bleeding ≥60 years old were randomly divided into two groups, 42 in the control group. Thrombin was injected into the gastric tube and ranitidine was intravenously injected. In the observation group, 43 cases were treated with intravenous injection of venom thrombin And ranitidine. The clinical efficacy, mean bleeding time and adverse reactions during the treatment were compared between the two groups. Results: The average time for stopping the gastrointestinal bleeding in the observation group was (16.8 ± 5.7) h, the total effective rate was 97.67%. The difference was statistically significant (P <0.05) compared with the control group, and no obvious adverse reactions occurred during the treatment . Conclusion: Ranitidine combined with snake venom thrombin injection in the treatment of elderly patients with gastrointestinal bleeding is effective, rapid, safe and reliable, it is worth promoting the use of.