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目的通过监测石家庄地区妊娠妇女不同妊娠期尿碘水平动态变化,及时纠正碘营养缺乏,避免新生儿出生缺陷,为科学防治提供可靠依据。方法于2010年3月—2012年12月,选取石家庄市8个居委会长期居住(外来人口在此居住1年以上者)的21~35岁单胎妊娠全程妇女344名。检测妊娠早、中、晚期尿碘水平。结果与妊娠早期比较,妇女妊娠中、晚期尿碘的中位数及碘超足量比例均较低,而碘缺乏的比例均较高,差异均有统计学意义(P<0.01)。学历、经济状况对孕妇不同妊娠期尿碘含量影响无统计学意义(P>0.05)。早、中、晚三期海产品摄入量2次及以上妊娠妇女尿碘含量均高于不足2次者,差异均有统计学意义(P<0.01)。结论石家庄地区妊娠期妇女妊娠早期碘营养处于适宜水平,但妊娠中、晚期却处于缺碘状态。
Objective To monitor the dynamic changes of urinary iodine in pregnant women in different gestation stages in Shijiazhuang and to correct the deficiency of iodine nutrition in time to avoid birth defects and provide a reliable basis for scientific prevention and treatment. Methods From March 2010 to December 2012, 344 women with singleton pregnancies of 21-35 years old who lived in 8 neighborhood committees in Shijiazhuang for a period of 1 year or longer were selected. Detection of early, middle and late pregnancy urine iodine levels. Results Compared with the first trimester of pregnancy, the median urinary iodine and iodine excess in pregnant women were lower than those in the first trimester, while the proportion of iodine deficiency was higher in both groups (P <0.01). Education, economic status of pregnant women in different gestational urinary iodine content was not statistically significant (P> 0.05). The levels of urinary iodine in the third, third, and third trimester of marine products intake of pregnant women were higher than those of less than twice, the difference was statistically significant (P <0.01). Conclusion Pregnant women in Shijiazhuang during the first trimester of iodine nutrition at an appropriate level, but in pregnancy, late but in a state of iodine deficiency.