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  5. Upregulation of MRTF-A pathway is involved in 17β-estradiol-stimulated migration of MCF-7 breast can

Upregulation of MRTF-A pathway is involved in 17β-estradiol-stimulated migration of MCF-7 breast can

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：taitaitaihaole
【摘 要】
：
Aim: Contrast to its proliferation activity on breast cancer, the effects of estrogen on breast tumor cell motility or invasion are more poorly understood.Here, the roles of MRTF-A pathway, the key do
【作 者】
：
Chun-ling ZHANG Xue-gang LUO Shu GUO Lei LIU Wen-wen ZHAO Ai MU Hao ZHOU Nan WANG Tong-cun ZHANG 
【机 构】
：
Key Laboratory of Industrial Fermentation Microbiology, Ministry of Education, College of Bioenginee
【出 处】
：
The 12th Meeting of the Asia Pacific Federation of Pharmacol
【发表日期】
：
2013年4期
【关键词】
：
17β-estradiol migration breast cancer cells MRTF-A SMYD3 
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Aim: Contrast to its proliferation activity on breast cancer, the effects of estrogen on breast tumor cell motility or invasion are more poorly understood.Here, the roles of MRTF-A pathway, the key downstream pathway of the Rho signaling, played in the 17β-estradiol (E2)-stimulated migration of MCF-7 breast cancer cells was investigated.
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