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  5. Bio-responsive microspheres for on-demand anti-inflammation and alveolar bone regeneration in period

Bio-responsive microspheres for on-demand anti-inflammation and alveolar bone regeneration in period

来源 :第三届国际纳米药物大会 ChinaNanomedicine 2018 The 3rd International Con | 被引量 : 0次 | 上传用户：littles721
【摘 要】
：
Herein,poly(L-lactic acid)(PLLA)nanofibrous spongy microspheres(NFSMS),PLLA/polyethylene glycol(PEG)co-functionalized mesoporous silica nanoparticles(MSN),and poly(lactic acid-co-glycolic acid)microsp
【作 者】
：
Xin Chen Zhongning Liu Peter X.Ma 
【机 构】
：
School of Chemical Engineering and Technology,Institute of Polymer Science in Chemical Engineering,S
【出 处】
：
第三届国际纳米药物大会 ChinaNanomedicine 2018 The 3rd International Con
【发表日期】
：
2018年7期
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论文部分内容阅读
　　Herein,poly(L-lactic acid)(PLLA)nanofibrous spongy microspheres(NFSMS),PLLA/polyethylene glycol(PEG)co-functionalized mesoporous silica nanoparticles(MSN),and poly(lactic acid-co-glycolic acid)microspheres(PLGA MS)are integrated into one multibiologic delivery vehicle for in situ Treg manipulation,where the MSNs and PLGA MS were utilized to distinctly release IL-2/TGF-β and miR-10a to locally recruit T cells and stimulate their differentiation into Tregs,while PLLA NF-SMS serve as an injectable scaffold for the adhesion and proliferation of these Tregs.
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