HAMPT,a novel quadruple drug combination designed for cancer metastatic chemoprevention:from hypothe

来源 :中国微米纳米技术学会纳米科学技术分会第四届年会暨2016国际纳米生物与医学学术会议 | 被引量 : 0次 | 上传用户:caoyouwen
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  HAMPT is a quardruple combination drug consisted of mifepristone,aspirin,lysine and doxycycline.It was specifically designed for synergistically controlling key cancer metastatic pathways.The dose of HAMPT was designed at lower than the pharmaceutically-recommended dose,and thus the sub-healthy cancer survivors may take HAMPT safely and long for metastasis chemoprevention.Based on our previous study,here,we further proved that HAMPT could effectively and safely prevent colon cancer metastasis.
其他文献
Phototherapy embodies two main therapeutic techniques: photothermal therapy(PTT)and photodynamic therapy(PDT).In these two techniques,the laser light energy could be converted into heat or highly reac
会议
Limulus amebocyte lysate(LAL)is the requested assay by regulatory authorities of United States of American and China for assessing endotoxin contamination in products for human use in vitro.However,it
Imaging-guided therapy is critically vital for cancer treatment [1,2],with aim to obtain better performance in application of cancer theranostics,a multifunctional Fe3O4@mSiO2@liposome nanocarrier(FML
RNA interference(RNAi)is emerging as one of promising strategies for tumor therapy,especially for inhibiting tumor metastasis [1].However,an efficient and safety non-virus delivery system for clinical
Block copolymer self-assembly provides a promising functional platform for constructing hierarchical mesoporous silica materials with uniform pore sizes ranging from 5~50 nm.Recently,more and more lab
会议
Cancer metastasis is frequently a lethal factor of cancer patients[1].Numerous literatures have reported that millions of cancer cells escape from the primary lesion everyday in the tumor sufferer.How
Targeted delivery of drugs to diseased tissues in vivo is important in cancer therapy to decrease side-effect resulting from nonspecific drug distribution and to enhance drug delivery efficiency.We ha
Cancer metastases caused by the circulating tumor cells(CTCs)is main reason in recurrence of cancer,which had also result in 90%of cancer death and the tendency to decrease of this situation didnt sho
会议