Synthesis,Characterization and Study of the Biological Effects of a Number of Iron Complexes on Prot

来源 :2008中国深圳蛋白质和多肽科学大会 | 被引量 : 0次 | 上传用户:wangyanling100wang
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  In biology,it is known that transition metal ions bind to proteins.Transition metal compounds play structural and catalytic roles in gene expression.The metalloregulatory proteins are a subclass that exerts metal-responsive control of genes involved in respiration,metabolism,and metal-specific homeostasis or stress-response systems,such as iron uptake and storage,copper efflux,and mercury detoxification.Two allosteric mechanisms for control of gene expression were first discovered in metalloregulatory systems:an iron-responsive translational control mechanism for ferritin production and a mercury-responsive DNA-distortion mechanismfor transcriptional control of detoxification genes.
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