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Background Radiofrequency catheter ablation of superior ventricular tachycardia (SVT) is unusual because of the anatomy.The aim of this study is to discuss the strategy of radiofrequency catheter ablation of SVT in patients with persistent left superior vena cava (PLSVC).Methods From June 2008 to June 2011, 17 patients with PLSVC and SVT underwent one of the following RFCA: AV node modification (8 patients), left accessory pathway (6 patients), paroxysmal atrial fibrillation (3 patients).