【摘 要】
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The issue of potential radiation related cardiac damage may also be assuming a new significance due to the widespread use of other cardiotoxic agents, such
【机 构】
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Mahak Hospital Iran
【出 处】
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(BITs 3rd Annual World Cancer Congress-2010, Breast Cancer C
论文部分内容阅读
The issue of potential radiation related cardiac damage may also be assuming a new significance due to the widespread use of other cardiotoxic agents, such as anthracyclines, paclitaxel and trastuzumab.Also, exceptionally, Bullous Pemphigoid (BP) may arise during radiotherapy.It is unclear which mechanism exactly triggers BP following megavoltage irradiation.The majority developed BP after RT and a median dose of 50Gy.Four patients developed BP during RT after a minimal dose of 20Gy.BP induced by RT was observed predominantly in patients with breast cancer.In all reported cases, there is a clear relationship with RT.Therefore, BP may be considered as RT-induced side effect.RT can induce a BP following a minimal dose of20Gy.Preclinical studies show that normal tissue radiation induced toxicity differs little with age.
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