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  5. In vivo assessment of hepatotoxicity, nephrotoxicity and biodistribution using 3-aminopropyltriethox

In vivo assessment of hepatotoxicity, nephrotoxicity and biodistribution using 3-aminopropyltriethox

来源 :International Conference on Nanoscience & Technology,China 2 | 被引量 : 0次 | 上传用户：shadowyin
【摘 要】
：
The biocompatibility and biodistdbution of magnetic nanoparticles (MNPs) in vivo are essential to ensure their safe clinical use.We have studied these aspects with our 3-aminopropyltdethoxysilanc-coat
【作 者】
：
Xiaowen Wang Jieying Zhang Xin Yang Zhenghai Tang Yanwen Hu Benke Chen Jintian Tang 
【机 构】
：
Institute of neurological disorders,Yuquan hospital,Tsinghua university,Beijing,100049,China
【出 处】
：
International Conference on Nanoscience & Technology,China 2
【发表日期】
：
2013年3期
【关键词】
：
magnetic nanoparticles biocompatibility magnetic induction hyperthermia biodistr 
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　　The biocompatibility and biodistdbution of magnetic nanoparticles (MNPs) in vivo are essential to ensure their safe clinical use.We have studied these aspects with our 3-aminopropyltdethoxysilanc-coated magnetic nanoparticles (APTS-MNPs) formulation, which can be used as magnetic induction hyperthermia media.Changes in tissue iron levels were analyzed over 4 weeks after intraperitoneal injection of APTS-MNPs to ICR mice.
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