Increased expression of the SPOP is related to poor prognosis in Nasophangeal Carcinoma

来源 :2015诺贝尔奖获得者医学峰会暨国际肿瘤研究高峰论坛 | 被引量 : 0次 | 上传用户:liaozhouyi
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  Objective To investigate the value of speckel-type POZ protein (SPOP) in nasopharyngeal carcinoma and to study whether it is a tumor metastasis promoting actor.Method SPOP expression was analyzed in 100-paraffin-embedded nasopharyngeal carcinoma issue with complete five-year follow-up and 20 normal nepsophayngeal tissue by immunohistochemical stainning.SPOP was found to be downregulated in nasopharyngeal carcinoma tissue compared to normal nasopharyngeal tissue.
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