Next generation of sequencing uncovers potential genetic driver mutations of pulmonary malignant gra

• 作 者: XUSong;ZHAOQing-chun;WUYi;WEISen;CHENJun;
• 机 构: Department of Lung Cancer Surgery, Lung Cancer Institute, Tianjin Medical University General Hospita
• 出 处: 2015诺贝尔奖获得者医学峰会暨国际肿瘤研究高峰论坛
• 发表日期: 2015年期

　　Objective Granular cell tumors (GCT) are uncommon, and usually benign neoplasms most commonly originated from tongue, skin, and breast.Malignant granular cell tumor (MGCT) which originally occurs in the lung is extremely rare.The presence of metastasis can differentiate malignancy from the benign ones.The genetic mechanism of MGCT is still not clear.