【摘 要】
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Encephalomyocarditis virus (EMCV) is a member of the Cardiovirus genus of the Picornaviridae family,with a single-stranded,positive-sense RNA genome of 7.8
【机 构】
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NationalResearchCenterForWildlifeBornDiseases,KeyLaboratoryofAnimalEcologyandConservationBiology,Ins
【出 处】
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The 5th International Conference on Rodent Biology and Manag
论文部分内容阅读
Encephalomyocarditis virus (EMCV) is a member of the Cardiovirus genus of the Picornaviridae family,with a single-stranded,positive-sense RNA genome of 7.8 kb in length.EMCV infects a broad range of species,including humans,worldwide.EMCV has been isolated from dozens of different species,and antibodies against it have been found in even more,although infection is often silent.Fatal outbreaks of EMCV-associated encephalitis and myocarditis have been reported in populations of swine,nonhuman primates,elephants,and other mammals,most typically in the captive setting of farms and zoos.The process of transmission is not well understood,but rodents are considered the natural reservoir for EMCV and the route of transmission is thought to be fecal–oral.This is supported by evidence connecting epizootics of EMCV with rodent infestation as well as data showing the slowing of outbreaks upon extermination of rodents.Further,the seroprevalence of EMCV varies by species of rodent and by geography.Several other species,both domestic and wild,are susceptible to EMCV,eg: red squirrel (Sciurusvulgaris leucourus) in Great Britain,from a pheasant (Phasianus colchicus) in Czechoslovakia,two dormice (Myoxus glis) in Italy.Wildlife seems to play an important role in EMCV infections.However,it is still unclear which wildlife species are involved and how transmission of infection to domestic animals occurs.
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