Age-associated cognitive decline, memory in particular, is a typical consequence of aging and an increasing biomedical concern, as over 38 million individua
Cardiovascular diseases continue to be the leading cause of death in all developed countries.Novel therapeutics for heart attacks, stroke, peripheral arteri
Despite meticulous adherence to presently known principles of surgical myocardial protection using advanced cardioplegic technologies, some patients require
The left atrial appendage is potentially a source of strokes in patients with atrial fibrillation.I will review the data suggesting LAA is a cause of stroke
Diabetes is associated with oxidative stress, mitochondrial damage and cardiac dysfunction.Mitochondrial aldehyde dehydrogenase (ALDH2) has shown some promi
We sought to determine if a common polymorphism can increase vulnerability to a modifiable risk factor for cardiovascular disease (CVD), and thereby influen
One of the purposes of developing health informatics is to enable the early detection, early diagnosis, and early treatment of diseases.Identified as one of
Channels selective for potassium ions come in many varieties, and have been adapted to many purposes.Most familiar are the signaling functions, such as repo
Last 5~6 years have been a period of revival of PET scanner and PET became an indispensible imaging tool for diagnosis of tumors and other metabolic abnorma
Appropriate regulation of the response to stress is critical for the maintenance of homeostasis.In mammals, the response is mediated by the hypothalamic-pit