论文部分内容阅读
磷酸酯取代的嘌呤核苷是我们课题组首次合成的一类新型核苷,也是首次在嘌呤碱基上引入C-P键.对测试核苷类化合物的抗病毒、抗癌药物活性对核苷类化合物的结构修饰具有重要的意义.
氧化碳-氢键活化合成新型磷酸酯取代的嘌呤核苷
【摘 要】
：
磷酸酯取代的嘌呤核苷是我们课题组首次合成的一类新型核苷,也是首次在嘌呤碱基上引入C-P键.对测试核苷类化合物的抗病毒、抗癌药物活性对核苷类化合物的结构修饰具有重要的意义.
【机 构】
：
新乡学院 化学化工学院 新乡 453000 河南师范大学 化学化工学院 新乡 453007
【出 处】
：
中国化学会第十届全国磷化学化工学术讨论会暨空间生命起源与进化专委会年会
【发表日期】
：
2015年7期
其他文献
HPLC is known as a common method to qualitative analysis and quantitative analysis,in this work,HPLC is used to separate and purify the folic acid which is a healthy care product with special helpful
会议
The screening and quantitation of pesticides in foods is one of the most demanding applications in food safety.
会议
ELIMINATING MATRIX EFFECTS DURING MULTI-RESIDUE PESTICIDE ANALYSIS BY EXTENSIVE DILUTION USING AGILE
Introduction The testing for pesticide residues in food products is the most important analysis in food safety.
会议
DETERMINATION OF 198 PESTICIDES IN VEGETABLES BY LIQUID CHROMATOGRAPHY/TRIPLE QUADRUPOLE MASS SPECTR
Pesticides are widely used in vegetable cultivation and pose a potential risk to human health.Recently,China government promulgated a more stringent National Food Safety Standard to restrict maximum r
会议
ON-LINE/IN-LINE COUPLING OF MICROEXTRACTION APPROACHES TO ATOMIC SPECTROMETRY FOR TRACE METAL ASSAYS
Over the past decade,novel sample preparation approaches embracing liquid-phase microextraction(LPME),micro-solid phase extraction(μSPE)and membrane-based separation approaches have emerged and rapidl
会议
VOLATILE SPECIES GENERATION AND ATOMIZATION FOR ATOMIC ABSORPTION AND ATOMIC FLUORESCENCE:NEW DEVELO
Generation of volatile species(VSG) of elements can substantially improve detection power of atomic spectrometry detectors since separation from the sample matrix and high efficiency analyte transfer
会议
Chemiluminescent and Fluorescent Methods for Detection of Functional Biomolecules and Therapeutic Mo
The detection of biomolecules with low abundance and the acquisition of ultra weak biological signals have been become a bottleneck of these fields.
会议
Coumarin derivatives have well displayed significant biological activities,includig pharmacological activities,anti-breast cancer,anti-HIV,anti-Alzheimer,vasorelaxant and platelet anti-aggregatory act
会议
Coumarin derivatives have well displayed significant biological activities,3-phosphorylated coumarins have also been exhibitted cetain cytotoxicity on some human leukemia cell1.An efficient AgNO3-cata
会议
五配位磷化合物在生物化学的发展中占有较特殊的地位,例如RNA的自体切割、ATP的能量转移、信息传导过程中蛋白的去磷酰化与磷酰化及酶活性调节等,其化学本质都是经过五配位磷化合物中间体来完成的.
会议