Understanding the reaction mechanism of Guanine(G)in DNA with oxidant radicals is imperative when trying to elucidate the potential oxidation damage on DNA.
Calcium is one of the major elements in human body,and critical in the biological and physiological functions.Soft tissue hardening due to calcification has
Bacillus possesses the peptide toxin Sporulation-Delaying Protein(SDP),which can kill cells within a biofilm to support continued growth,thereby delaying th
G protein-coupled receptors(GPCRs)comprise the largest family of integral membrane proteins.They function as signal messengers and play crucial roles in var
In structure-based drug design,automated de novo design methods are helpful tools for lead discovery as well as lead optimization.In a previous study(J.Chem
Alzheimer's disease(AD)is associated with the aggregation of the amyloid-beta(Aβ)peptides into toxic aggregates.How to inhibit the aggregation of Aβ pepti
The first step in most viral infections is the penetration of the cell membrane via endocytosis.However,the underlying mechanism of this important process h