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The Ministry of Agriculture,Forestry and Fisheries (MAFF) carded out the first 5-year nanotechnology project "Development of Nanotechnology and Materials for Innovative Utilizations of Biological Functions" between FY2002 and FY2006.The project is composed of 6 teams:"Development of nano-structured tissue culture plates"; "Development of process technology for monodisperse nanoparticles and their utilization such as in a drug delivery system"; "Development of new functional biomaterials by controlling molecular orientation and so forth"; "Development of technologies for nano-scale analysis and modification of biomolecules"; "Evaluation and utilization of dynamic states of water cluster" and "Development of micro-bioreactor system".The project has obtained several excellent results and achieved 512 research papers and 68 patents.