ASIC1a channel mediates neuronal necroptosis independent of its ion conducting function

来源 :The 4th International Ion Channel Conference(第四届国际离子通道会议) | 被引量 : 0次 | 上传用户：zlongtime

【摘要】

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【作者】

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Tian-Le Xu Yi-Zhi Wang

【机构】

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Shanghai Jiao Tong University School of Medicine, China

【出处】

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The 4th International Ion Channel Conference(第四届国际离子通道会议)

【发表日期】

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2013年2期

【关键词】

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necroptosis non-conducting function of ion channel ASIC1a

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Necrosis is an important form of cell demise during organ development and diseases.Traditionally, necrosis has been considered as an accidental, uncontrolled form of cell death.Increasing evidence now shows that the execution of necrotic cell death may be carried out by a set of signal transduction pathways and execution mechanisms (thus termed as necroptosis).

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ASIC1a channel mediates neuronal necroptosis independent of its ion conducting function

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