Assessing the Effects of Nitric Oxide on Cellular Bioenergetics in Neuronal Cells

来源 :2013第四届国际神经科技大会 | 被引量 : 0次 | 上传用户:G00G01
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  Neuronal Cells are highly energetic and as such are susceptible to modification by reactive oxygen and nitrogen species.This is particularly important under conditions of neuronal excitation where increased calcium influx into the cell leads to the activation of nitric oxide synthase.An important example is stroke where we hypothesized that the combined stress of hypoxia and high levels of NO can lead to bioenergetic dysfunction.
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