【摘 要】
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This talk will summarize our work on analysis of MR brain images.Our main research goal is to develop auto mated image analysis methods for precisely quantifying subtle and complex structural/ functio
【机 构】
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Department of Radiology, University of Pennsylvania, Philadelphia, PA
【出 处】
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第五届21世纪中美医学论坛(The 5th Sino-US Symposium on Medicine in the 2
论文部分内容阅读
This talk will summarize our work on analysis of MR brain images.Our main research goal is to develop auto mated image analysis methods for precisely quantifying subtle and complex structural/ functional changes in the brains, to be used for early detection of brain diseases, such as Alzheimers Disease (AD).Accordingly, we de veloped a 3D brain registration method, called HAMMER, which has been successfully applied to many large clini cal research studies and clinical trials involving-5,000 MR brain images.In order to measure the tiny longitudi nal brain changes, i.e., due to AD, we also have developed a 4D (3 spatial dimensions + 1 temporal dimension) brain registration algorithm and obtained more accurate measurement results, compared to those by 3D registration algorithm.
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