Oral administration of levo-tetrahydropalmatine attenuates reinstatement of extinguished cocaine see

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  Cocaine addiction is characterized by a persistently heightened susceptibility to drug relapse.For this reason, the identification of medications that prevent drug relapse is a criti cal goal of drug abuse research.Drug re-exposure, the onset of stressful life events, and exposure to cues previously associated with drug use have been identified as determinants of relapse in humans and have been found to reinstate extinguished drug see king in rats.
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