内皮型一氧化氮合酶(eNOS)基因多态性与特发性弱精症关联性研究

来源 :GTAUF2014 & APSMHA2014第六届长城泌尿男科转化医学论坛暨第七届亚太男性健康与抗衰老研究学会年会 | 被引量 : 0次 | 上传用户：sammerkong

【摘要】

：

目的:许多男性不育的病因不明,然而,弱精症作为一种常见的特发性男性不育,应该更加受到关注.目前证实,有大量与精子运动性相关的基因,与突变相比,基因多态性在特发性弱精症中可能扮演了一个非常重要的作用.资料显示NO在精子发生过程中发挥着巨大的作用,而NO水平潜在影响人类精子的运动性.除了内皮细胞,NO合酶(eNOS)也表达了在支持细胞和生殖细胞.由于其广泛表达在人类睾丸的多种类型的细胞,因此eNOS与

【作者】

：

宋平平邹沙沙肖倩陈剑华温祖佳宋智健李铮胡洪亮

【机构】

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上海交通大学医学院附属仁济医院泌尿外科,上海市男科学研究所,精子发育与遗传学实验室,上海市人类精子库,上海200135,中国

【出处】

：

GTAUF2014 & APSMHA2014第六届长城泌尿男科转化医学论坛暨第七届亚太男性健康与抗衰老研究学会年会

【发表日期】

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2014年11期

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