Deubiquitinase Regulates TCR signaling

来源 :中国免疫学会第十届全国免疫学学术大会 | 被引量 : 0次 | 上传用户：shiguanglai

【摘要】

：

　　Ubiquitination has been reported as one of major regulating mechanisms of T-cell activation.Studies on Cbl, ITCH and GRAIL have highlighted that the ubiquit

【作者】

：

Hongbo Hu Hui Wang Yichuan Xiao Jin Jin Shao-Cong Sun

【机构】

：

State Key Laboratory of Biotherapy,West China Hospital,Si-Chuan University and Collaborative Innovat

【出处】

：

中国免疫学会第十届全国免疫学学术大会

【发表日期】

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2015年期

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　　Ubiquitination has been reported as one of major regulating mechanisms of T-cell activation.Studies on Cbl, ITCH and GRAIL have highlighted that the ubiquitin E3 ligases play critical roles in maintaining the balance of T-cell activation and tolerance.

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Deubiquitinase Regulates TCR signaling

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