Tim-3/Gal-9 pathway activation ameliorates renal ischemia reperfusion injury by shifting the balance

来源 :中国免疫学会第十届全国免疫学学术大会 | 被引量 : 0次 | 上传用户：johnlu888

【摘要】

：

　　Background: Activation of CD4+T cells play a pivotal role in renal ischemia reperfusion injury.Galectin-9 (Gal-9) is a T-cell immunoglobulin domain and T mu

【作者】

：

YameiWang;YuhongTao;

【机构】

：

Department of pediatrics,West China Second University hospital,Sichuan University

【出处】

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中国免疫学会第十届全国免疫学学术大会

【发表日期】

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2015年期

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　　Background: Activation of CD4+T cells play a pivotal role in renal ischemia reperfusion injury.Galectin-9 (Gal-9) is a T-cell immunoglobulin domain and T mucin domain protein-3 (Tim-3) ligand, and Tim-3/Gal-9 interaction acts as a specific inhibitor of immune response.

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Tim-3/Gal-9 pathway activation ameliorates renal ischemia reperfusion injury by shifting the balance

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