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MicroRNAs (MiRNAs) are small non-coding RNA molecules which act as important regulatorsof post-transcriptional gene expression by binding 3-untranslated region (3-UTR) oftarget mRNA.In this study, we analyzed miRNA-34a (miR-34a) as a tumor suppressor innon-small cell lung cancer (NSCLC) H1299 cell line.