上皮性卵巢癌化学治疗临床进展

来源 :中华医学会第十四次全国妇科肿瘤学术会议 | 被引量 : 0次 | 上传用户:liongliong426
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近年来,在国际妇科医师的协作努力下,卵巢癌的化学治疗取得了一定的进展.基于现有的循证医学证据,早期卵巢癌无高危因素者无需术后辅助化疗,晚期卵巢癌标准治疗仍为肿瘤细胞减灭术及术后铂类为基础的联合化疗;腹腔化疗可延长满意的肿瘤细胞减灭术后患者生存时间,但难于普及推广应用,尚不能取代传统静脉化疗;新辅助化疗可减少围手术期并发症的发生,提高手术成功率,但不能改善长期生存;巩固化疗可延长患者PFS,但OS亦无改善,不建议常规临床应用.尽管众多新型化疗药物不断应用于临床,但均无证据显示其可替代目前的标准一线化疗方案,多用于二线、三线化疗
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