Characteristics of 5-Fu, CPT-11, and VP-16 on other cell lines under intervention therapy environmen

来源 :22nd Asia Pacific Cancer Conference(第22届亚太抗癌大会) | 被引量 : 0次 | 上传用户:xingyu2266
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Objective: To determine whether a concentration-and timedependent phenomenon for 5-Fu, CPT-11, and VP-16 exists in cell lines.Method: MTT assay was used to detect the inhibition rate of the combination of different concentrations and acting time in all agents.Five concentrations were chosen within the range of clinical practice in interventional therapy (20∶10∶5∶2∶1),whereupon the highest concentrations were 160, 8, and 8 mg/L.Each concentration of the agents acted with HepG-2 and 7702cell lines for 2, 4, 6, 8, and 24 h.
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