The Effect of Overexpression of Sarco/endoplasmic Reticulum Ca2+-ATPase (SERCA2a) on Endoplasmic Ret

来源 :2015中国老年医学和老年健康产业大会 | 被引量 : 0次 | 上传用户：leongiggs

【摘要】

：

【作者】

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Z.G.Qu X.C.Lu X.Y.Li X.H.Liu F.F.Xu Y.Qu

【机构】

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Department of Geriatric Cardiology, Chinese PLA General Hospital, Beijing, China;Department of Overs

【出处】

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2015中国老年医学和老年健康产业大会

【发表日期】

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2015年7期

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OBJECTIVE: Overexpression of SERCA2a attenuates unfolded protein response (UPR), and decreases the tissue and systemic inflammation markers in heart failure animal models.This study aimed to investigate the effect of overexpression of SERCA2a on endoplasmic reticulum stress (ERS) induced NF-κB activation in neonatal rat cardiomyocytes.

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