蛔虫抗原对Th17细胞的影响及抗肿瘤作用的初步探讨

来源 :中国免疫学会第九届全国免疫学学术大会 | 被引量 : 0次 | 上传用户：lwm1976

【摘要】

：

目的:探讨Th17细胞在蛔虫抗原诱导的人肺腺癌细胞株(A549)凋亡中的作用机制.方法:收集新鲜蛔虫虫体,制备蛔虫抗原.选定低、中、高三个蛔虫抗原浓度分别作用A549细胞1h,18h和24h,其中A549细胞和T淋巴细胞采用共培养体系.用流式细胞术、ELISA和qPCR分别检测蛔虫抗原作用A549细胞后细胞凋亡率的变化及Th17细胞相关细胞因子表达的变化和mRNA的表达水平.

【作者】

：

黄川杨志黄艳琴胡银英戴志芳袁芳袁铿

【机构】

：

南昌大学医学院;江西省医学科学研究院江西省医学科学研究院

【出处】

：

中国免疫学会第九届全国免疫学学术大会

【发表日期】

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2014年8期

【关键词】

：

蛔虫抗原 T细胞 Th17细胞 A549细胞凋亡

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蛔虫抗原对Th17细胞的影响及抗肿瘤作用的初步探讨

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