MKP-1 up-regulation attributed to depression-like behavior in UT-B null mice

来源 :The 18th Congress of the International Federation of Associa | 被引量 : 0次 | 上传用户：wzw919

【摘要】

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【作者】

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Jianhua Ran Jinfang Li Hongkai Wang

【机构】

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Department of Anatomy, College of Medicine,the Second Affiliated Hospital, Chongqing Medical Univers

【出处】

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The 18th Congress of the International Federation of Associa

【发表日期】

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2014年8期

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Urea accumulation in hippocampus caused by urea transporter B (UT-B) deletion could induce depression-like behavior in mice with unknown mechanism.MKP-1 was reported to be increased in depression patients, serves as a regulator of L-arginine/urea metabolism as well thereby we explore the role of MKP-1 in depression-like behavior of UT-B null mice.

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MKP-1 up-regulation attributed to depression-like behavior in UT-B null mice

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