Title: A Novel Oil-based Formulation for Oral Delivery of Peptides

来源 :2015年中国药物制剂大会、中国药学会药剂专业委员会2015年学术年会暨国际控释协会中国分会2015年学术年会 | 被引量 : 0次 | 上传用户:yinhongtao2009
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Poor permeability, strong polarity and low stability in the GI tract of peptides limit their administration routes and formulation designs which require delivery by frequent injections.Various approaches to develop oral delivery systems have been currently receiving a lot of interest.
其他文献
  Biodegradable poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) containing interferon (IFN) α-2b were loaded in chitosan-based thermosensitive hydro
会议
  To improve the oral bioavailability of nanocrystalline drug preparations, the cationic 12-3-12 quaternary ammonium surfactant Gemini was introduced into nan
会议
  Introduction: Oxymatrine (OM) is a kind of alkaloid extracted from a Chinese herb, which has been found to possess anti-hepatic fibrosis effect, but its ant
会议
  Basic Fibroblast Growth Factor (bFGF) is a cytokine that plays an important role in cell proliferation,tissue development, and angiogenesis.It is widely use
会议
会议
  Matched filter NIR laser optical video systems,as developed by Strickler,have been mostly used in laboratories to study live copepod behaviors.In situ,optic
会议
会议
  The Anguillid eel is a nutritious and delicious food resource for people.Most of the eels consumed are from the aquaculture of glass eels that are caught fr
会议
  In this study, we prepared a multifunctional oligosaccharides of hyaluronan (oHA) conjugates,oHA-histidine-menthone 1,2-glycerol ketal (oHM).The oHM conjuga
会议
  The development of paediatric medicines can be challenging since this is a diverse patient population with specific needs.Acceptable palatability of oral pa
会议