Glibenclamide improves survival and neurological outcome after cardiac arrest in rats

来源 :The 6th FAONS Congress and 11th Biennial Conference of CNS(第 | 被引量 : 0次 | 上传用户：taiguomin

【摘要】

：

Glibenclamide(GBC)confers neuroprotection in animal models as well as retrospective clinical studies.This study determines whether GBC improves outcome after cardiac arrest in rats.

【作者】

：

Kaibin Huang Yong Gu Yafang Hu Zhong Ji Shengnan Wang Zhenzhou Lin Xing Li Zuoshan Xie Suyue Pan

【机构】

：

Department of Neurology,Nanfang Hospital,Southern Medical University,Guangzhou,510515

【出处】

：

The 6th FAONS Congress and 11th Biennial Conference of CNS(第

【发表日期】

：

2015年3期

【关键词】

：

glibenclamide cardiac arrest cardiopulmonary resuscitation necrosis apoptosis cy

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Glibenclamide(GBC)confers neuroprotection in animal models as well as retrospective clinical studies.This study determines whether GBC improves outcome after cardiac arrest in rats.

其他文献

Electroencephalographic (EEG) Measurements of Long-Term Meditators:A Pilot Study

Introduction Alpha rhythm is an EEG correlate for a state of relaxed wakefulness best obtained with eyes closed,generally with higher voltage over occipital region.

会议

meditationmind relaxationEEG

Stereo processing in macaque visual area MT probed by graded anti-correlation of binocular stimuli

The visual system represents binocular disparity in correlation-based and match-based manners.In correlation-based representation,disparity is computed by the spatial cross-correlation between the lef

会议

binocular stereopsisneural representationbinocular disparity tuningMT

Chronic fluoxetine treatment induces morphological changes of the perforant path synapse in the dent

A selective serotonin reuptake inhibitor(SSRI)is the most commonly prescribed antidepressants for the treatment of major depression.

会议

SSRIDentate GyrusFIB-SEMsynaptic morphology

Possible protective role of Ceylon tea on Spinocerebellar Ataxias-A pilot study

Introduction-Spinocerebellar ataxias(SCAs) are a group of heterogeneous neurodegenerative disorders.Compromised oxidative stress defense capacity and mitochondrial dysfunction due to cytoplasmic and n

会议

spinocerebellar ataxiasteageneticsSri Lanka

Vulnerable vasculature and increased inflammation contribute to earlier death and higher mortality a

Type 1 diabetic patients are found to be more prone to cerebrovascular mortality from stroke in epidemiological studies,with half median survival when compared with those in the general population.

会议

strokeblood-brain barrierautophagy

Sphingosine kinase 1 mediates neuroinflammation following cerebral ischemia

Sphingosine kinases(Sphks) are the rate-limiting kinases in the generation ofsphingosine-1-phosphate,which is a well-established intracellular pro-survival lipidmediator.

会议

cerebral ischemiasphingosine kinase 1neuroinflammationmicroglia

The effects on the memory function by the hippocampal neurons autophagy and endoplasmic reticulum st

Objective To investigate the effects of hippocampal neurons autophagy and endoplasmic reticulum stress(ERS)on the memory function of mice after focal cerebral ischemia-reperfusion(I-R),and the possibl

会议

brainischemia-reperfusion (I/R)endoplasmic reticulum stress (ERS)autophagy4-

Electro-acupuncture increases the proliferation of neural progenitor cells in the cortical peri-infa

Objective: Electro-acupuncture(EA)is a novel therapy based on combining traditional acupuncture with modern electrotherapy,and is currently being investigated as a treatment for ischemic stroke.

会议

electro-acupuncturecerebral ischemiaWnt/β-cateninneural progenitor cells (NPC

Activation of mGluR4 attenuates oxidative stress-induced death of neural stem cells through inhibiti

Objective Neural stem cell(NSC)replacement promises a novel therapeutic strategy for stroke and other brain diseases.However,this approach is impeded possibly due to the hostile brain environments whi

会议

metabotropic glutamate receptor 4neural stem cellsoxidative stresshydrogen pe

miR-181c-TRIM2 pathway is involved in cognitive deficiency induced by chronic cerebral ischemia/hypo

Objective Chronic cerebral ischemia is a serious threat to human health.Recent studies indicate particular miRNA changes in response to ischemia/hypoxia brain damage.

会议

miR-181cTRIM2ischemia/ hypoxiacognitive impairment

Glibenclamide improves survival and neurological outcome after cardiac arrest in rats

其他学术论文