Sphingosine kinase 1 mediates neuroinflammation following cerebral ischemia

来源 :The 6th FAONS Congress and 11th Biennial Conference of CNS(第 | 被引量 : 0次 | 上传用户：fyf7228912

【摘要】

：

Sphingosine kinases(Sphks) are the rate-limiting kinases in the generation ofsphingosine-1-phosphate,which is a well-established intracellular pro-survival lipidmediator.

【作者】

：

Jian Cheng Jia Jia Shuli Zheng Shanwen Wei Xiaoyu Wang Yingxiu Xu Yunqi Xiao Hui Liu

【机构】

：

Jiangsu Key Laboratory of Translational Research and Therapy for Neuro-Psycho-Diseases and Institute

【出处】

：

The 6th FAONS Congress and 11th Biennial Conference of CNS(第

【发表日期】

：

2015年3期

【关键词】

：

cerebral ischemia sphingosine kinase 1 neuroinflammation microglia

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Sphingosine kinases(Sphks) are the rate-limiting kinases in the generation ofsphingosine-1-phosphate,which is a well-established intracellular pro-survival lipidmediator.

其他文献

Impact of tea and coffee consumption on stroke and Parkinson disease:A Sri Lankan perspective

会议

strokePDteacoffeesmoking

Layer-specific heterogeneity of astrocytes in the mouse neocortex

会议

astrocyteheterogeneityneocortexmorphology

Interaction between glia cells and lung cancer cells in microenvironment of brain metastases

Metastasis is the principal cause of the morbidity and death of cancer patients.Brain metastases occur in about 25%of all cancer patients,in which the most common primary lesion was reported to be lun

会议

lung cancerastrocytemicrogliametastasisVandetanib

Role of caudal superior colliculus in microsaccades generation:tested using electrical microstimulat

会议

microsaccadesmonkeyssuperior colliculusmicrostimulation

Ultra-rapid generation of genome-edited mice crucial for neurodevelopmental research via CRISPR/Cas9

Gene knockout mice and gene knockin mice are pivotal tools for studying higher-order life phenomenon in vivo,and also important for drug discovery as disease models.

会议

Genome editingCRISPR/Cas9Pax6cadherins

Electroencephalographic (EEG) Measurements of Long-Term Meditators:A Pilot Study

Introduction Alpha rhythm is an EEG correlate for a state of relaxed wakefulness best obtained with eyes closed,generally with higher voltage over occipital region.

会议

meditationmind relaxationEEG

Stereo processing in macaque visual area MT probed by graded anti-correlation of binocular stimuli

The visual system represents binocular disparity in correlation-based and match-based manners.In correlation-based representation,disparity is computed by the spatial cross-correlation between the lef

会议

binocular stereopsisneural representationbinocular disparity tuningMT

Chronic fluoxetine treatment induces morphological changes of the perforant path synapse in the dent

A selective serotonin reuptake inhibitor(SSRI)is the most commonly prescribed antidepressants for the treatment of major depression.

会议

SSRIDentate GyrusFIB-SEMsynaptic morphology

Possible protective role of Ceylon tea on Spinocerebellar Ataxias-A pilot study

Introduction-Spinocerebellar ataxias(SCAs) are a group of heterogeneous neurodegenerative disorders.Compromised oxidative stress defense capacity and mitochondrial dysfunction due to cytoplasmic and n

会议

spinocerebellar ataxiasteageneticsSri Lanka

Vulnerable vasculature and increased inflammation contribute to earlier death and higher mortality a

Type 1 diabetic patients are found to be more prone to cerebrovascular mortality from stroke in epidemiological studies,with half median survival when compared with those in the general population.

会议

strokeblood-brain barrierautophagy

Sphingosine kinase 1 mediates neuroinflammation following cerebral ischemia

其他学术论文