Synaptic Plasticity of Midbrain Dopamine Neurons

来源 :2014第五届国际神经科技大会暨2014首届国际高科技针灸和中西医结合大会 | 被引量 : 0次 | 上传用户:gxp_crysta1
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  Midbrain dopamine neurons participate in reward-learning and formation of drug addiction.Single or repeated exposure to drugs of addiction lead to long lasting changes in excitatory transmission on dopamine neurons of ventral tegrnental area (VTA).We recently found that GluN3A-containing NMDA receptors are inserted at VTA synapses after single dose of cocaine injection, accompanying a switch of synaptic calcium sources.
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