BDNF stimulates the survival, expansion, and differentiation of human spinal cord neural stem cells

来源 :The 18th Congress of the International Federation of Associa | 被引量 : 0次 | 上传用户：chenyongze

【摘要】

：

【作者】

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Liyan Li Jianhui Guo Jinwei Yang Jin Ru Yongsheng He Jia Liu

【机构】

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Kunming Medical University, Yunnan Kunming 650500,China

【出处】

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The 18th Congress of the International Federation of Associa

【发表日期】

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2014年8期

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BDNF has critical function in promoting survival,differentiation and proliferation of Neural stem cells, but its downstream regulation mechanism is still not fully understood.In order to explore whether BDNF can play a role by Wnt/β-catenin pathway in human embryonic spinal cord NSCs, we successfully cultured hESC-NSCs and found the number, area and differentiation of NSCs were increased after transfected by pIRES2-ZsGreen1-BDNF plasrnid.

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BDNF stimulates the survival, expansion, and differentiation of human spinal cord neural stem cells

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