Low density lipoprotein peptide conjugated submicron emulsions for combating prostate cancer

来源 :2015年中国药物制剂大会、中国药学会药剂专业委员会2015年学术年会暨国际控释协会中国分会2015年学术年会 | 被引量 : 0次 | 上传用户：posedong

【摘要】

：

　　Submicron emulsions (SEs) is an advanced formulation that possesses good biocompatibility, high loading of hydrophobic drugs, and good stability through aut

【作者】

：

PengchaoSun[1]NanZhang[1]QianLiang[1]HaiyingHua[2]XiaoxueZhang[1]QianSun[1]YongxingZhao[1]

【机构】

：

Department of Pharmaceutics, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou,HeNa

【出处】

：

2015年中国药物制剂大会、中国药学会药剂专业委员会2015年学术年会暨国际控释协会中国分会2015年学术年会

【发表日期】

：

2015年期

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　　Submicron emulsions (SEs) is an advanced formulation that possesses good biocompatibility, high loading of hydrophobic drugs, and good stability through autoclave sterilization.To enhance tumor targeting and tumor cell uptake, SEs could be modified with positive charge and targeting moieties.In the present study, three formulations were prepared: Docetaxel-loaded SEs (DocSEs), cationic DocSEs (DocCSEs), and low density lipoprotein receptor (LDLR) targeted peptide-RLT modified DocCSEs (RLT-DocCSEs).

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Low density lipoprotein peptide conjugated submicron emulsions for combating prostate cancer

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