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目的:探讨未折叠蛋白反应(UPR)信号转导通路与再灌注肺凋亡的关系。方法:采用C57BL/6J小鼠在体单侧肺原位缺血再灌注损伤模型。实验小鼠140只,随机分为14组,每组10只:假手术组(sham组)、缺血再灌注组(I/R组)、磷酸盐缓冲
Objective: To investigate the relationship between the unfolded protein reaction (UPR) signal transduction pathway and the reperfusion lung apoptosis. Methods: C57BL / 6J mice were used to study the model of orthotopic lung ischemia-reperfusion injury in vivo. 140 mice were randomly divided into 14 groups (n = 10): sham group, I / R group, phosphate buffered saline