Oxidative stress and DNA Methylation mediated the anatase titanium dioxide nanoparticles-induced the

• 作 者: WenlinBai;YujiaoChen;JingYang;LiChen;LefengZhang;JunxiangMa;LinTian;PiyeNiu;AiGao;
• 机 构: Department of Occupational Health and Environmental Health,School of Public Health,Capital Medical U
• 出 处: 全国卫生毒理学术研讨会
• 发表日期: 2014年期

　　Objective To observe the mechanisms of the abnormal expression of miR34a and miR133a induced by the anatase titanium dioxide nanoparticles(TNPs 25nm).Methods AHH-1 cells were treated with the anatase titanium dioxide nanoparticles for 24h,Real time PCR method was used to detect the expression of miR34a and miR133a.