Protective effect of betulinic acid on dexamethasone induced lymphocyte apoptosis by reducing oxidat

来源 :中国畜牧兽医学会兽医内科与临床诊疗学分会第八届代表大会暨学术研讨会 | 被引量 : 0次 | 上传用户：viviane_px349

【摘要】

：

【作者】

：

ZHU Ruocen XIA Wei TAN Zhuliang YI Jin'e

【机构】

：

College of Veterinary Medicine, Hunan Agricultural University, Changsha 410128,P.R.China

【出处】

：

中国畜牧兽医学会兽医内科与临床诊疗学分会第八届代表大会暨学术研讨会

【发表日期】

：

2015年4期

【关键词】

：

dexamethasone betulinic acid oxidative stress lymphocyte apoptosis

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　　[Backgroud]Dexamethasone (Dex), a synthetic glucocorticoid, is strictly controlled for use due to its serious side effects including immune suppression.Betulinic acid (BA), an antioxidant prepared from the white birch, exhibits properties of immunomodulation.To assess the implications and investigate the mechanisms of BA-elicited immunomodulation, we hypothesized that Dex induced lymphocyte apoptosis via oxidative stress could be lessened by BA.

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Protective effect of betulinic acid on dexamethasone induced lymphocyte apoptosis by reducing oxidat

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