【摘 要】
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Two-dimensional electrophoresis is the best tool for discovering pharmacodynamic action and influene of different drugs on cells.We applied this methodology
【机 构】
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OMIInstituteforAnthropologicalMedicineSlovenia
【出 处】
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2008中国深圳蛋白质和多肽科学大会
论文部分内容阅读
Two-dimensional electrophoresis is the best tool for discovering pharmacodynamic action and influene of different drugs on cells.We applied this methodology in search for explanation of mechanism of action of anti addictive drug Ibogaine.Ibogaine is an indole alkaloid present in the root of the plant Tabemanthe iboga.It is known to attenuate abstinence syndrome in animal models of drug addiction.Since the anti-addiction effect lasts longer than the presence ofibogaine in the body,some profound metabolic changes are expected.
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