Protective Effects and Mechanisms of 1,25-dihydroxyvitamin D3 in a Rat MCAO Model of Cerebral ischem

• 作 者: YanqiangWang;LeiZhang;YinyaoLin;ZhengqiLu;
• 机 构: Department of Neurology, The Third Affiliated Hospital of Sun Yat-sen University,Guangzhou, Guangdon
• 出 处: 广东省医学会第十七次神经病学学术会议暨第七届粤港澳神经病学学术会议
• 发表日期: 2015年期

　　Objective: The inflammation and immune response, are a key contributor to the pathogenesis of ischemic stroke (IS).Accumulating reports demonstrate that Vitamin D(3) has the multifaceted immunomodulatory effects, notably the expansion of Tregs and the decrease of Th9, Th1 and Th17 cells, in inflammatory and autoimmune diseases.However, there is still a lack of data about the effects of Vitamin D(3) in immune regulation in ischemic stroke.