The upregulation of angiotensin Ⅱ--AT1 receptor reducing ICC loss mediated by PI3k/AKT signaling pat

来源 :中国生理学会第24届全国会员代表大会暨生理学学术大会 | 被引量 : 0次 | 上传用户:dong0003060
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Objectives:Angiotensin Ⅱ (AngⅡ),as local hormone in gastrointestinal tract,plays an important role inregulation of smooth muscle motility and smooth muscle proliferation.However,it is not clear whetherAng Ⅱ is involved in diabetics-induced loss of gastric ICC.
其他文献
In mammals including the human beings,the neural control of airway smooth muscles is dominated by medullary airway vagal preganglionic neurons (AVPNs),especially those located in the external formatio
Background:Hypoxia-induced pulmonary hypertension (PH) is a serious disorder characterized by activation of hypoxia inducible factor-1 (HIF).MicroRNAs play a significant role in modulating vascular re
探讨内脏痛敏及艾灸疗效与骨髓HSP70、TRPV1 表达的关系。方法:SD 乳鼠结直肠扩张(CRD)7 天,8周时进行CRD 刺激记录腹部撤回反射(AWR)及测痛阈,观察艾灸(每天1 次,共7 天)效应,分为对照(1组)、艾灸大肠俞模型(2 组)、艾灸非穴位模型(3 组)及非艾灸模型组(4 组)。
Background:Physiological functions of endogenous hydrogen sulfide (H2S),as a neuromodulator in central nervous system attract much attention recently.Previous studies clue to us that H2S plays importa
Objectives:Hydrogen sulfide (H2S) has been proposed as a gasotransmitter similar to nitric oxide (NO) and carbon monoxide (CO).It has been proved to play important biologic roles in the regulation of
Objectives:Angiotensin Ⅱ (AngⅡ) as local hormone in gastrointestinal tract play an important role in regulation of smooth muscle motility and smooth muscle proliferation.However,it is not clear whethe
BACKGROUNDS & AIMS:Except acid secretion,gastric parietal cells can also produce a substantial amount of dopamine (DA).In vivo study has suggested the involvement of DA in the gastric acid secretion,b
The present study aimed to investigate the protective effect and the mechanism of hydrogen sulfide (H2S) against gastric mucosal injury induced by gastric ischemia-reperfusion (GI-R) in rats.The rats
Nesfatin-1 is an anorexigenic brain-gut peptide discovered in 2006.The previous studies about nesfatin-1 focused on hypothalamus and brainstem circuits which implicated in feeding regulation.Recently,
Objectives:H2S has been shown to have an excitatory effect on gastric motility,but the underlying molecular mechanism is unclear.In this study,we aimed to investigate the possible targets of H2S and h