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it is obvious that fight against microorganisms is constant challenge in the world.The methods recently applied for inactivation of food pathogens are not always efficient,human and ecologically friendly.Consequently,foodbome diseases have been estimated to cause billions of illnesses,millions of hospitalizations and thousands of deaths each year.Hence,much remains to be done in this area.In this context photosensitization might serve as really promising antibacterial tool.Materials and Methods:this treatment involves the administration of a photoactive compound (prodrug aminolevulinic acid,10-3m) that selectively accumulates in the target microorganism (107cfu/ml)and after 15-30 min.