A systematic molecular dynamics approach to the study of peptide Keap1-Nrf2 protein-protein interact

• 作 者: Hai-Shan Zhou Qi-Dong You Zheng-Yu Jiang
• 机 构: State Key Laboratory of Natural Medicines, China Pharmaceutical University,Nanjing 210009, China
• 出 处: 2016年长三角药物化学研讨会
• 发表日期: 2016年11期

　　Protein-protein interactions (PPIs) as drug targets have been gaining growing interest,though developing drug-like small molecule PPI inhibitors remains challenging.Peptide PPI inhibitors,which can provide informative data on the PPI interface,are good starting points to develop small molecule modulators.