论文部分内容阅读
The presence of multiple homologs of the same Atg gene in multicellular organisms confers a layer of complexity on the more elaborate autophagic machinery.However, very little is known about the differential function of these homologs in the autophagy pathway.Here we demonstrated that the two C.elegans Atg8 homologs, encoded by Igg-1 and Igg-2, are differentially employed in the autophagy pathway in a tissue-, time-and substrate-specific manner.