ANEPⅢ, a new recombinant neurotoxic peptide that inhibits N-methyl-D-aspartic acid ligand-gated and

• 作 者: Chunli Li Wenshu Huang Jinghai Zhang Yongbo Song Yanjie Lu Chunfu Wu
• 机 构: Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang 110016, Liaoning Province,
• 出 处: 2nd International Neural Regeneration Symposium(INRS2012)(第二
• 发表日期: 2012年8期
• 关键词: recombinant ANEP (ANEPⅢ) excitotoxicity glutamate intracellular Ca2+concentratio

　　The effects of ANEPⅢ, a new recombinant neurotoxic peptide, on behavior and brain neuronal activity in animal studies have previously been described.However, whether ANEPⅢ can directly protect neurons against neuroexcitation damage and the molecular mechanisms underlying these effects are poorly understood.