Clonidine improves cognitive deficits by regulating synaptic strength in chronic cerebral hypoperfus

• 作 者: Changjun Li Yun Lu Qing Lv Xulin Xu Lianjun Guo
• 机 构: Department of Pharmacology, School of Basic Medical Sciences, Tongji Medical College, Huazhong Unive
• 出 处: 2nd International Neural Regeneration Symposium(INRS2012)(第二
• 发表日期: 2012年8期
• 关键词: clonidine chronic cerebral hypoperfusion cognition LTP HCN1/HCN2

　　Permanent bilateral occlusion of the common carotid arteries in rats is an established experimental model to investigate chronic cerebral hypoperfusion on cognitive function and neurodegenerative processes.